Can i take allegra d while pregnant




















Selective histamine H 2 blockers have been used in all trimesters with no known teratogenic effects. In a meta-analysis of 2, women taking H 2 blockers, the OR for congenital malformations was 1. Proton pump inhibitors recently became available OTC. Although concerns have been raised about the potential teratogenicity of omeprazole Prilosec , multiple large cohort studies have demonstrated its safety when taken before conception and during the first trimester.

Proton pump inhibitors and H 2 blockers are considered safe in pregnancy. Diarrhea and constipation are common during pregnancy. Products containing bismuth, mineral oil, and castor oil should be avoided. Bismuth itself is safe, but it has the same risks as aspirin when combined with salicylate. Although the American Gastroenterological Association considers loperamide to be low risk, it should be avoided when possible until further information is available.

Considered safe in pregnancy; magnesium may cause tocolysis in late pregnancy, but this is not a risk with over-the-counter preparations. Simethicone available as a single agent and contained in multiple combination antacids. Sodium salicylate is not thought to suppress platelet function like the salicylate moiety found in aspirin; however, given the concerns over potential fetal toxicity from chronic salicylate exposure, avoidance in the latter half of pregnancy may be prudent.

Data Sources : We searched PubMed, UpToDate, the National Guideline Clearinghouse, and the Cochrane database using the terms over-the-counter, medicine, and pregnancy; herbals and pregnancy; and individual drug names in combination with pregnancy. Search dates: February to July , July The authors thank pharmacist Stephanie Owens for querying the Clinical Pharmacology database.

The opinions herein are those of the authors. Already a member or subscriber? Log in. Interested in AAFP membership? Learn more. Reprints are not available from the authors. Medication use during pregnancy, with particular focus on prescription drugs: — Am J Obstet Gynecol.

Labeling and prescription drug advertising; content and format for labeling for human prescription drugs. Federal Register.

Food and Drug Administration. Summary of proposed rule on pregnancy and lactation labeling. Accessed June 28, Use of over-the-counter medications during pregnancy. Fetal safety of drugs used in the treatment of allergic rhinitis: a critical review. Drug Saf. The safety of asthma and allergy medications during pregnancy. J Allergy Clin Immunol. Pregnancy outcome following first trimester exposure to antihistamines: meta-analysis.

Am J Perinatol. Use of antihistamine medications during early pregnancy and isolated major malformations. Weber-Schoendorfer C, Schaefer C. The safety of cetirizine during pregnancy. Reprod Toxicol. Philadelphia, Pa. Placental transfer and fetal metabolic effects of phenylephrine and ephedrine during spinal anesthesia for cesarean delivery. Werler MM. Teratogen update: pseudoephedrine. Physicians' Desk Reference. Accessed July 27, Clinical Pharmacology.

National Library of Medicine. Daily Med. Association of sympathomimetic drugs with malformations. Vet Hum Toxicol. Case-control study of a gastroschisis cluster in Nevada. Arch Pediatr Adolesc Med. Maternal medication use and risks of gastroschisis and small intestinal atresia. Am J Epidemiol. Maternal medications and environmental exposures as risk factors for gastroschisis. A case control study to examine the pharmacological factors underlying ventricular septal defects in the North of England.

Eur J Clin Pharmacol. Ferencz C, et al. The Baltimore-Washington Infant Study, — Armonk, NY: Futura Publishing; Use of oral decongestants during pregnancy and delivery outcome. Decongestant use during pregnancy and its association with preterm delivery. Clinical inquiries. Is guaifenesin safe during pregnancy? J Fam Pract. The safety of dextromethorphan in pregnancy: results of a controlled study.

What over-the-counter preparations are pregnant women taking? A literature review. J Adv Nurs. A review of the literature on the effects of acetaminophen on pregnancy outcome. Case-control analysis of maternal prenatal analgesic use and cardiovascular malformations: Baltimore- Washington Infant Study [published ahead of print March 27, ]. Accessed August 7, Paracetamol in pregnancy and the risk of wheezing in offspring: a systematic review and meta-analysis.

Clin Exp Allergy. Acetaminophen use during pregnancy: effects on risk for congenital abnormalities. Maternal use of acetaminophen, ibuprofen, and acetylsalicylic acid during pregnancy and risk of cryptorchidism. Acetaminophen use during pregnancy, behavioral problems, and hyperkinetic disorders. JAMA Pediatr. Acetaminophen in pregnancy and future risk of ADHD in offspring. Can Fam Physician. Acetaminophen use in pregnancy and risk of birth defects: findings from the National Birth Defects Prevention Study.

Obstet Gynecol. Aspirin and reproductive outcomes. Obstet Gynecol Surv. Aspirin consumption during the first trimester of pregnancy and congenital anomalies: a meta-analysis.

Periconceptional over-the-counter nonsteroidal anti-inflammatory drug exposure and risk for spontaneous abortion. Nonsteroidal anti-inflammatory drugs in early pregnancy. Herbal use before and during pregnancy. Dietary supplements. Accessed July 30, Conover EA.

Over-the-counter products: nonprescription medications, nutraceuticals, and herbal agents. Clin Obstet Gynecol. Evaluating the safety of St. John's Wort in human pregnancy. Pregnancy outcome following gestational exposure to echinacea: a prospective controlled study. Arch Intern Med. Herb remedies during pregnancy. This study provides reassurance that the OTC antihistamine, Allegra not Allegra-D though , may be safe in use during pregnancy.

Keep in mind that intranasal sprays have been shown to be superior to oral antihistamines for rhinitis treatment. Rhinocort budesonide is considered safe during pregnancy as well. Is Clarinex safe during Pregnancy? Fish Oil Supplementation during Pregnancy. Food intake and Allergy during Pregnancy. Pregnancy and Asthma. Some oral antihistamines, like Allegra fexofenadine , Benadryl diphenhydramine , Chlor-Trimeton chlorpheniramine , Claritin loratadine , and Zyrtec cetirizine appear to be safe after the first trimester, safe meaning they have caused no known harm in studies that have been done.

Avoid antihistamines combined with a decongestant. Most have a D for decongestant after the name, like Claritin-D. Nasal sprays, as prescribed or recommended by a doctor, are applied only in the nose. That means their effects do not go throughout the body like oral medications. However, avoid nasal spray decongestants. There is not enough evidence to indicate whether or not they are safe. If women are already taking them when they become pregnant, they can continue. The reality is, not taking any allergy medication is the best option.

Uncontrolled asthma can cause serious problems during pregnancy. Primarily, pollens in the air cause spring allergies. Pollens come primarily from trees and grasses.



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